The most important step to avoid shadows and spill is to light the screen and the subject separately, using different sets of lights. You want to create a uniform and even illumination on the screen, without any hotspots or dark areas. You can use soft lights, such as fluorescent tubes or LED panels, and place them on both sides of the screen, at a 45-degree angle. You should also use a light meter or a waveform monitor to check the exposure and color balance of the screen, and adjust the intensity and position of the lights accordingly. You want to aim for a brightness level of around 50% on the waveform monitor, and a green value of around 40-60% on the vectorscope.
For the subject, you want to create a natural and flattering lighting that matches the background you will use. You can use a three-point lighting setup, consisting of a key light, a fill light, and a backlight. The key light is the main source of light, and it should be placed on the opposite side of the screen, at a 45-degree angle from the subject. The fill light is a softer light that fills in the shadows created by the key light, and it should be placed on the same side of the screen, at a lower angle and intensity than the key light. The backlight is a light that creates a rim of light around the subject, and it should be placed behind and above the subject, at a 45-degree angle from the screen. The backlight helps to separate the subject from the screen and reduce spill, but it should not be too bright or too close to the subject, as this can create unwanted highlights or flares.