Acknowledgement and validation must come before contention or confrontation, as the latter two never end well. Interrupters are often natural attention seekers, it's best to give them what they want in a professional manner. Dig in deep and find a way to weave their perspective into your speech, which further helps calm any egotistical tendencies at play. If none of these work, try silence, and 9 times out of 10, they eventually retreat, with the full glare of the audience on them. No one wants to be embarrassed, not even the interrupter.

One thing I have found useful is to listen actively to the interrupter. Address the point in a respectful manner. Speaker can also ask other audience if they also hold similar thoughts. Depending on the answer speaker can have further conversation. In case of repeated interruption, I would politely say that your question is valid and hold it for Q&A session. Or you may also say that you have covered his point in subsequent communication, if that is the case. Sometimes, Public speaking can present some unexpected situations. It's important to stay calm and composed. Different situations may require different ways to address such audience.

??If someone keeps interrupting you during your speech, the key is to stay calm and in control. First, pause, smile, and make eye contact with the interrupter - this shows confidence. Then, politely say something like, “I'll get to that soon, but let me finish this point first.” This sets boundaries without being rude.

After having respectfully acknowledged the interrupter twice, manage the interruption with poise, presence and power. For instance: Time: It would give me great pleasure to turn this into a discussion. Unfortunately, I am not in control of the schedule. May I ask you to hold all further questions and comments until the end. If I do not get to answer them in a Q&A, I will ensure to follow up. Content: It would give me great pleasure to turn this into a discussion, but I must pay due respect to the organisers and attendees, and cover the content planned. Could you please hold...(as above). Continued interruption: I have requested that further comments be held. Please allow me to continue. (Repeat this unchanged if pressed thereafter).

Hot(ish) Take: Bull. By. The. Horns. Name the problem, name the person; they're likely seeking attention, so take control and give it to them... On your terms. AFTER you've set clear expectations that are not being followed, AFTER you've politely acknowledged their point, AFTER you've shown patience, I recommend calmly but assertively interrupting the interrupter, asking their name (maybe walk the mic right up to them to show you mean business), and remind them that your Q&A session starts in approximately X minutes. There is little value in subtlety when hundreds, maybe thousands, are watching. This "problem" could be a phenomenal opportunity for you to demonstrate to the audience why they should listen to every word after.