Encryption in use means that your data is encrypted when it is processed or accessed by an application or a service in the cloud, such as a web app, a machine learning model, or a database query. This way, even if someone infiltrates your cloud environment, they cannot access your data in plain text without the encryption key. Encryption in use is the most challenging and advanced form of encryption, as it requires special techniques and technologies, such as homomorphic encryption, secure multiparty computation, or trusted execution environments, that allow performing operations on encrypted data without decrypting it. The advantage of using encryption in use is that it provides the highest level of security and privacy for your data, as it eliminates any exposure or vulnerability at any stage of the data lifecycle. The disadvantage is that it is still an emerging and experimental field, with limited availability, scalability, and efficiency.