However, using 6LoWPAN for low-power wireless devices also has some drawbacks. First, it introduces some challenges and trade-offs in terms of performance, reliability, and scalability. For example, header compression may increase the processing time and complexity of low-power devices, fragmenting IPv6 packets may cause more packet loss and retransmissions, and routing IPv6 packets may require more memory and computation resources. Second, it requires some adaptation and coordination with other protocols and standards, such as IEEE 802.15.4, CoAP, RPL, and ND. For example, 6LoWPAN has to deal with the different frame sizes, link layers, and addressing schemes of these protocols, as well as the interactions and dependencies among them. Third, it faces some limitations and uncertainties in terms of deployment, adoption, and evolution. For example, 6LoWPAN may not be compatible with some legacy or proprietary systems, may not be widely supported by some vendors or platforms, and may be affected by the changes and updates of the IPv6 protocol and its extensions.