There are different formats for 2D animations on the web, such as GIF, SVG, CSS, Canvas, and WebGL. Each format has its own advantages and disadvantages, depending on the complexity, color, transparency, and interactivity of your animation. For example, GIF is a simple and widely supported format, but it has a limited color palette and can result in large file sizes. SVG is a scalable vector format that can handle high-resolution and interactive animations, but it can be difficult to animate and render. CSS is a fast and lightweight way to animate HTML elements, but it has limited support for complex shapes and effects. Canvas and WebGL are powerful formats that can create rich and dynamic animations, but they require more coding and processing power. You should choose the format that best suits your animation's needs and goals, and test it on different browsers and devices.