Python is a dynamic, interpreted, and high-level language that offers many features and libraries for system design, but also has some drawbacks, such as the lack of static type checking, indentation-based syntax, and global interpreter lock. To debug Python systems effectively, you need to use a combination of tools and methods. For instance, powerful and interactive debuggers like pdb or ipdb allow you to inspect and modify variables, execute commands, set breakpoints, and trace exceptions. Additionally, frameworks such as unittest, pytest, or nose can be used for writing unit tests and integration tests to verify the functionality and performance of your code. Moreover, logging and printing useful information like inputs, outputs, exceptions, and timestamps can help track the execution flow and the state of your system. Lastly, code analysis tools such as pylint, flake8, or mypy can check your code for syntax errors, style violations, and potential bugs while suggesting improvements and best practices.