The second step to create a research question is to develop a question that reflects your topic and interest. A research question is a specific and focused inquiry that you want to answer through your research. To develop a research question, you can use the PICO model to define the key elements of your question, such as the population, intervention, comparison, and outcome. For instance, if your topic is mental health and your interest is mindfulness, you can ask: How does mindfulness affect the mental health of college students compared to other interventions? Alternatively, you can use the SPICE model to frame your question in terms of the setting, perspective, intervention, comparison, and evaluation. Additionally, the W questions strategy can help you generate questions based on who, what, when, where, why, and how. For example, if your topic is technology and your interest is artificial intelligence, you can ask: How does artificial intelligence influence the ethical decision-making of human professionals?