Here's how you can guarantee accurate and reliable results with new technology in the laboratory.

Ensure accurate and reliable results with new technology in the laboratory by validating, calibrating, training staff, implementing quality control measures, maintaining equipment, and documenting procedures meticulously.

Automation can bring a lot of value but there is an associated risk. Processes will be running with less hands-on intervention, freeing up resources and reducing the amount of labor expended on the task. When implementing automation, you will be frontloading a lot of the work to get the system running through debugging, iterative optimization, and validation of robust systems controls. The more hands off the system is, the more complex it usually is, requiring more specialized training. Additionally, tolerance stacking is a big problem. The problem may not manifest in 30 cycles, but after 100 cycles your product may no longer meet specifications. Always assess how much automation you need, and when it's too much for your capabilities.

Automation adds value, more work gets done ensuring that turn around times are met-One of the key performance indicators for medical laboratories. That ensures the client receives their results in reasonable set time frames.

In my experience the most important method that we can ensure about accurate and reliable results is validation. when the validation method was used, we can sure about our results. moreover, it is essential to use auto-sampler in HPLC devices.

Maintain collaborative friendships with colleagues that promotes better access to innovative and increased accuracy in the laboratory. Group discussions always helps to learn what your contemporaries are doing. Shared Information is King!

When talking about high performance laboratory equipment, I think something that is underemphasized is the ability to financially support that equipment. In the case of HPLC versus UHPLC, you have to be prepared to support higher consumable costs. The obvious aspect is the solvents, which need to be higher purity to compensate for the increased sensitivity and resolution of the systems. The less transparent issue is in the columns. No matter what anyone tells you about how far along the solid phase technology has come, they wear out faster and are more expensive to replace. This is true with every component of the system. What you really need to do when buying new equipment is assess if that extra precision will measurably benefit you.

I've never worked on an instrument that constantly produces 100% reproducibility rates. Shifts, biases, trends and outliers constantly occur. The performance of any system wears off from time to time depending on what principles that instrument uses: Photometry, flowcytometry, colometry etc. and all these need to be corrected or calibrated a certain way to ensure the system operates the way it is intended to. They also need to be maintained as per supplier instructions to ensure efficiency, Then tested through internal quality control and external quality control to monitor its performance. The proficiency schemes are essential in ensuring accurate and precise patient results.

The major laboratory instrument suppliers saw this as a need: to be able to troubleshoot remotely by giving application specialists and engineers access to instruments remotely in real time. Thus making it easier to resolve problems remotely and cutting unnecessary costs related to traveling eg. flights, fuel and hotel costs.

Addition of new technology to the laboratory is always exciting, and the people working with the equipment directly can quickly observe that value. However, the education shouldn't end with the direct users. The new capabilities introduced with new technology have to be shared up and down stream. For example, if you purchase new preparative liquid chromatography equipment, your analytical teams should know if they need more sensitive methods to support the new equipment. On the other side, your sales team should know what throughput capabilities you can offer to your clients. The reach of new technology will ripple through your company in many ways.

This is still one of the hardest things to do, to get technical staff members to improve their technical knowledge abilities: the fear of troubleshooting is a common issue faced in many laboratories. This often points to a lack of adequate training with the majority only stopping their training at the basic user stage. Most instrument providers allow for technical employers to get trained up to super user stage. A necessary requirement to ensure problems are addressed efficiently, reducing down time.